Efficacy of Pregabalin as Premedication for Post-Operative Analgesia in Vaginal Hysterectomy

efficacy of pregabalin as premedication for post-operative analgesia in vaginal hysterectomy

conclusions pregabalin administered as premedication provided significant postoperative pain relief and decreased the requirement of other parenteral analgesics. pregabalin doses of 150 mg had a better analgesic profile, but the advantages of their use may be limited by side effects such as dizziness. thus, it is concluded that pregabalin doses of 75 mg may be the optimal pre-emptive dose. back...

Efficacy of Pregabalin as Premedication for Post-Operative Analgesia in Vaginal Hysterectomy

BACKGROUND Pregabalin, a structural analogue of gamma amino butyric acid (GABA), is shown to be effective in treatment of several types of neuropathic pain, incisional injury, and inflammatory injury. OBJECTIVES The aim of the present study is to compare the efficacy of two doses (75 mg or 150 mg) of pregabalin with the administration of a placebo for post-operative analgesia in patients unde...

Effect of Oral Pregabalin Premedication on Post-Operative Pain in Laparoscopic Gastric Bypass Surgery

BACKGROUND Post-operative pain and the administration of opioids to relieve it, is considered to be one of the important issues in surgery wards. This issue is even more significant in obese patients, because of the side effects of opioids. Pregabalin is an analog of gamma aminobutyric acid (GABA) which can be effective in dealing with post-operative pain. OBJECTIVES This study will consider ...

effect of oral pregabalin premedication on post-operative pain in laparoscopic gastric bypass surgery

conclusions the findings of this study indicate that oral pregabalin (300 mg dose) can alleviate patients’ pain and nausea/vomiting and notably reduce adverse effects. results a total of 60 patients were compared; 30 patients in each of the pregabalin and control groups. both groups were similar in age and sex distribution. mean pain intensity levels during the whole follow up were lower in the...

Novel concepts of analgesia for post operative pain: Multimodal analgesia